Ten very hard questions on how Fentanyl, Methamphetamine, Alcohol, and MDMA hijack the synapse, plus a five-minute team challenge to draw the mechanism of serotonin syndrome.
MechanismToleranceWithdrawalBonus Challenge
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10 Questions + Bonus Challenge
The Synapse Under Siege
Read clinical vignettes and work backwards to the disrupted system. Distinguish reverse-transporter mechanisms (meth, MDMA) from receptor-level disinhibition (opioids), and the dual-action of alcohol on GABA-A and NMDA. 60 seconds per question. The bonus challenge gives teams 5 minutes to draw the mechanism behind a deadly drug interaction. Tap to start.